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Carcinogenesis of β-Propiolactone: A Computational Study.

Eva Španinger1, Urban Bren1

  • 1Laboratory of Physical Chemistry and Chemical Thermodynamics, Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ulica 17, SI-2000 Maribor, Slovenia.

Chemical Research in Toxicology
|February 15, 2020
PubMed
Summary

Beta-propiolactone (BPL) can damage DNA, but glutathione may protect against its harmful effects. Computer simulations reveal how BPL reacts with DNA bases and glutathione.

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