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Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...

Pericarditis I: Introduction

Pericarditis I: Introduction

Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...

Pleural Effusion I: Introduction

Pleural Effusion I: Introduction

Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...

Pleural Effusion II: Symptoms and Management

Pleural Effusion II: Symptoms and Management

Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:

Pericarditis III: Medical Management

Pericarditis III: Medical Management

The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...

Pericarditis IV: Nursing Management

Pericarditis IV: Nursing Management

Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.

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Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

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Valproic acid associated pleuropericardial effusion: case report.

Ulku Figen Demir¹

¹Neurology Department of Istanbul Yeni Yüzyıl University Medical School, Istanbul.

Ideggyogyaszati Szemle

|February 15, 2020

Summary

Valproic acid, an antiepileptic drug, rarely causes pleuropericardial effusion. This rare side effect resolved after discontinuing valproic acid treatment in a young woman.

Area of Science:

Neurology
Cardiology
Pharmacology

Background:

Valproic acid is a widely used antiepileptic and mood-stabilizing medication.
Common side effects are known, but rare complications require attention.
Pleural and pericardial effusions are infrequent adverse events associated with valproic acid therapy.

Observation:

A 23-year-old woman developed dyspnea after one year of valproic acid treatment for epilepsy.
Diagnostic workup for dyspnea was unremarkable, leading to suspicion of drug-induced etiology.

Findings:

Pleuropericardial effusion was diagnosed in the patient undergoing valproic acid therapy.
Discontinuation of valproic acid led to complete resolution of the effusion within 1.5 months.

Keywords:

pleuropericardial effusion valproic acid

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Implications:

Pleuropericardial effusion is a rare but potential adverse effect of valproic acid.
Clinicians should consider valproic acid as a potential cause of pleuropericardial effusion when other etiologies are ruled out.