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Updated: Dec 28, 2025

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Real-Time Imaging of CCL5-Induced Migration of Periosteal Skeletal Stem Cells in Mice
Published on: September 16, 2020
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Mid-term migration pattern of a calcar-guided short stem: A five-year EBRA-FCA-study
Karl Philipp Kutzner1, Emanuel Ried2, Stefanie Donner1
1Department of Orthopaedic Surgery and Traumatology, St. Josefs Hospital Wiesbaden, Beethovenstr. 20. 65189 Wiesbaden, Germany.
Summary
Mid-term results show calcar-guided short stems achieve stable fixation in most patients. However, male and heavy-weight patients face increased risk of axial migration, with undersizing noted in unstable cases.
Area of Science:
- Orthopedic surgery
- Biomedical engineering
- Implant migration analysis
Background:
- Short-stem hip implants often lack mid- and long-term migration data.
- Early axial migration has been observed in some short-stem designs.
Purpose of the Study:
- To evaluate the mid-term (5-year) migration pattern of a specific calcar-guided short stem.
- To identify factors influencing stem migration and stability.
Main Methods:
- 191 calcar-guided short stems were assessed using Ein-Bild-Roentgen-Analysis Femoral-Component-Analysis (EBRA-FCA) at 5 years.
- Migration patterns were analyzed and compared between groups based on early subsidence, Dorr types, age, gender, weight, BMI, and surgical laterality.
- Varus and valgus stem alignment outcomes were also assessed.
Main Results:
- Mean axial subsidence was 1.5 mm at 5 years.
- 73 stems were "at hazard" (subsidence >1.5 mm at 2 years), with 69 achieving secondary stabilization.
- Male gender, heavy weight, and valgus alignment were associated with higher axial migration risk; undersizing was noted in 4 unstable cases.
Conclusions:
- Calcar-guided short stems generally achieve stable fixation by 5 years, even in stems initially showing migration.
- Male and heavy-weight patients are at increased risk for continued subsidence.
- While clinical consequences remain uncertain, stem undersizing may contribute to instability.
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