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Tick-borne encephalitis in Serbia: A case series
Jasmina Poluga1, Aleksandra Barac2, Natasa Katanic3
1Clinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade, Serbia. poluga@eunet.rs.
Journal of Infection in Developing Countries
|February 15, 2020
Summary
Tick-borne encephalitis (TBE) is increasing in Europe. This study analyzed 10 Serbian patients, finding half had severe illness but no deaths, highlighting the need for TBE serological testing in CNS infections.
Area of Science:
- Neurology
- Infectious Diseases
- Epidemiology
Background:
- Tick-borne encephalitis (TBE) incidence and endemic areas are growing across Europe.
- Serbia experienced a TBE virus epidemic in 2017.
Purpose of the Study:
- To present clinical and socio-epidemiological data of hospitalized TBE patients during an epidemic in Serbia.
- To emphasize the importance of TBE diagnosis in central nervous system infections.
Main Methods:
- A case series of 10 confirmed TBE patients in Serbia during 2017.
- Inclusion of biochemical, serological (blood and CSF), and radiological (CT, MRI) analyses.
Main Results:
- The study included 10 patients (1.5:1 M:F ratio, average age 45.1 years).
- Half presented with severe clinical TBE; imaging was largely unremarkable except in one severe case.
- Mildly elevated inflammatory markers (CRP, sedimentation) and CSF pleocytosis/protein were observed.
Conclusions:
- TBE diagnosis is crucial due to overlapping symptoms with other CNS infections.
- Routine serological testing for TBE is recommended for patients with central nervous system infections.
