A Extensively drug-resistant Pseudomonas putida bacteremia that was resolved spontaneously

Area of Science:

• Medical Microbiology
• Infectious Diseases
• Clinical Case Reports

Background:

• Pseudomonas putida (P. putida) is an opportunistic pathogen, rarely causing infections, primarily in immunocompromised hosts like newborns, neutropenic, and cancer patients.
• Increasing antibiotic resistance in P. putida strains poses a growing clinical challenge.
• While generally considered less virulent than Pseudomonas aeruginosa, P. putida can cause severe, even fatal, infections.

Observation:

• A case of P. putida infection following an invasive procedure in a patient with gastrointestinal malignancy is presented.
• The patient developed antibiotic-resistant bacteremia due to P. putida.

Findings:

• The P. putida bacteremia resolved spontaneously without requiring antibiotic treatment.
• This suggests P. putida may exhibit lower virulence and distinct antibiotic susceptibility profiles compared to Pseudomonas aeruginosa in certain clinical contexts.

Implications:

• This case underscores the need for further clinical data to fully understand P. putida's virulence and antibiotic resistance patterns.
• Clinicians should consider P. putida in the differential diagnosis of infections, especially in at-risk populations.
• The spontaneous resolution warrants further investigation into host factors and bacterial characteristics influencing infection outcomes.