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Guillain-Barré syndrome complicated by takotsubo cardiomyopathy: an under-recognised association

Timothy Jones1, Neelan Umaskanth2, James De Boisanger2

  • 1Northwick Park Hospital, London North West University Healthcare NHS Trust, Harrow, London, UK timothy.jones@imperial.ac.uk.

BMJ Case Reports
|February 16, 2020
PubMed

A 41-year-old woman was admitted with progressive paraesthesia and weakness and was diagnosed with Guillain-Barré syndrome. Following an initial period of recovery with intravenous immunoglobulin treatment, she developed acute chest pain associated with electrocardiographic changes. Investigations excluded acute coronary syndrome and instead confirmed a diagnosis of takotsubo cardiomyopathy, which was treated medically. The patient made an excellent neurological and cardiac recovery. Here we discuss the rarely described association between these two conditions and suggest that patients admitted with Guillain-Barré syndrome may benefit from routine screening with echocardiography.

Keywords:
cardiovascular medicineclinical neurophysiologyheart failureneuromuscular diseaseperipheral nerve disease

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