Glimpses into the future of rabies research

Much is now known about the chemical composition of the rabies virus but little is known of its pathogenesis. Techniques used commonly in molecular biology research can and should be applied to questions about the behavior of the rabies virus and the responses of the challenged host so that new generations of vaccines may be produced. The vaccinia-rabies glycoprotein recombinant vaccine acts by inducing neutralizing antibody to rabies virus and completely protects various species of vaccinated animals against challenge with rabies virus. The vaccinia-rabies glycoprotein recombinant vaccine is the most promising of the new generation of rabies serums.