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Lumbar arachnoiditis: Does imaging associate with clinical features?

Vincent Parenti1, Fahimul Huda2, Perry K Richardson3

  • 1The George Washington University School of Medicine and Health Sciences, 2300 I St. NW, Washington, DC, 20052, USA.

Clinical Neurology and Neurosurgery
|February 17, 2020
PubMed
Summary
This summary is machine-generated.

Magnetic resonance imaging (MRI) findings in lumbar arachnoiditis generally do not correlate with clinical symptoms. However, confounding lumbar pathology and nerve root contour showed some associations with clinical presentation.

Keywords:
AdhesionArachnoiditisCauda equinaDelamarterLumbar spineMRI

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Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Lumbar arachnoiditis is a rare neurological disorder with diverse causes and varied clinical and imaging features.
  • Previous anecdotal reports suggested no link between magnetic resonance imaging (MRI) findings and clinical assessments of lumbar arachnoiditis.

Purpose of the Study:

  • To investigate the association between MRI characteristics and clinical findings in patients with lumbar arachnoiditis.

Main Methods:

  • Retrospective analysis of 28 patients with lumbar arachnoiditis diagnosed via MRI between 2012 and 2018.
  • Cataloging of MRI features (nerve root contour, adhesion location, enhancement) and clinical data (demographics, etiology, symptoms).
  • Statistical analysis using Fisher's exact tests to identify correlations.

Main Results:

  • Most MRI findings did not correlate with clinical features of lumbar arachnoiditis.
  • Confounding lumbar pathology was associated with symptom dynamics (p=0.004).
  • Nerve root contour on MRI correlated with motor and sensory symptoms (p=0.01).
  • Post-operative and post-infectious causes were most common.

Conclusions:

  • MRI findings provide limited insight into the clinical presentation of lumbar arachnoiditis.
  • Specific imaging features may offer some predictive value for certain symptoms.