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Osteoporosis in Scheuermann's disease.

R A Lopez1, S W Burke, D B Levine

  • 1Department of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.

Spine
|October 1, 1988
PubMed
Summary
This summary is machine-generated.

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Scheuermann's disease is strongly linked to osteoporosis, with patients showing significantly lower bone mineral density (BMD) in the lumbar spine and femoral neck compared to healthy individuals. This association, particularly in severe kyphosis cases, warrants further investigation into medical management strategies.

Area of Science:

  • Orthopedics
  • Radiology
  • Endocrinology

Background:

  • Scheuermann's disease is a spinal condition characterized by increased thoracic kyphosis.
  • Osteoporosis, a condition of reduced bone mineral density (BMD), poses significant health risks.
  • The relationship between Scheuermann's disease and osteoporosis requires further elucidation.

Purpose of the Study:

  • To prospectively evaluate the prevalence and extent of osteoporosis in adolescent patients diagnosed with thoracic Scheuermann's disease.
  • To compare bone mineral density (BMD) in patients with Scheuermann's disease to age-, sex-, height-, and weight-matched controls.
  • To investigate the correlation between the degree of kyphosis and bone density in these patients.

Main Methods:

  • A prospective study involving ten untreated patients with thoracic Scheuermann's disease (mean age 16 years, mean kyphosis 64 degrees).

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  • Bone mineral density (BMD) was quantified using single and dual photon absorptiometry.
  • Comparison was made with seven age-, sex-, height-, and weight-matched healthy controls.

    • Main Results:

    • Patients with Scheuermann's disease exhibited significantly lower mean BMD in the lumbar spine (0.975 vs. 1.130, P<0.025) and femoral neck (1.00 vs. 1.22, P<0.005) compared to controls.
    • In patients with kyphosis >45 degrees, BMD was significantly reduced in the lumbar spine (0.913, P<0.005) and femoral neck (0.983, P<0.005).
    • Radius BMD was not significantly different in the overall patient group but was significantly lower in those with kyphosis >45 degrees (0.655, P<0.01).

    Conclusions:

    • A highly significant association exists between osteoporosis and Scheuermann's disease.
    • Reduced bone mineral density is evident in the lumbar spine and femoral neck of patients with Scheuermann's disease, especially with severe kyphosis.
    • Further research is recommended to explore the role of medical interventions for osteoporosis in patients with Scheuermann's disease.