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Report of the National Heart, Lung, and Blood Institute Working Group on Hypertension: Barriers to Translation

Curt D Sigmund1, Robert M Carey2, Lawrence J Appel3

  • 1From the Department of Physiology, Medical College of Wisconsin, Milwaukee (C.D.S.).

Hypertension (Dallas, Tex. : 1979)
|February 18, 2020
PubMed

Insights

Researchers identified key barriers and opportunities for translating hypertension research into improved patient care. This aims to bridge the gap between basic science discoveries and clinical application for better hypertension management.

Area of Science:

  • Cardiovascular Research
  • Translational Science
  • Hypertension Management

Background:

  • The National Heart, Lung, and Blood Institute (NHLBI) convened experts to address challenges in hypertension research.
  • Focus on translating basic science discoveries into clinical practice and patient care.

Purpose of the Study:

  • To review recent hypertension discoveries ready for testing.
  • Identify knowledge gaps impeding research translation.
  • Highlight promising areas for translational research.
  • Address barriers in moving discoveries to clinical studies and trials.
  • Identify roadblocks for implementing research findings in real-world settings.

Main Methods:

  • Multidisciplinary working group meeting.
  • Discussion and synthesis of current scientific knowledge in hypertension.
  • Identification of barriers and opportunities in research translation.

Main Results:

  • Major barriers and opportunities for translating hypertension research were identified.
  • The working group's discussions aligned with NHLBI Strategic Vision objectives.
  • Key challenges in moving basic science to clinical application were highlighted.

Conclusions:

  • Effective translation of hypertension research is crucial for improving patient outcomes.
  • Addressing identified barriers can accelerate the implementation of evidence-based hypertension care.
  • Continued focus on translational science is needed for advancing hypertension management.

Keywords:
clinical trialgoalsimmunologyknowledgescience

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