Related Experiment Video
Updated: Dec 28, 2025

06:46
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
586
High Cancer Risk in US Naval Personnel Serving in Nuclear Powered Ships.
1Environmental Research SIA, 1117 Latvian Academy of Sciences, Riga, Latvia.
Cancer Investigation
|February 18, 2020
Summary
Serving on nuclear-powered ships like the USS Ronald Reagan may pose a significant cancer risk to sailors. This finding contrasts with current radiation protection guidelines, suggesting a need for reassessment.
Area of Science:
- Naval health research
- Radiation oncology
- Epidemiology
Background:
- Nuclear-powered warships present unique occupational health challenges.
- Assessing long-term health outcomes for naval personnel is crucial.
- Previous studies may not fully capture risks associated with naval nuclear propulsion.
Purpose of the Study:
- To evaluate cancer incidence among sailors serving on a nuclear-powered aircraft carrier.
- To compare cancer risks in nuclear-ship sailors against a matched control group.
- To determine if current radiation protection models adequately predict observed cancer risks.
Main Methods:
- Retrospective cohort study utilizing 2014 Defense Threat Reduction Agency data.
- Analysis included 4,843 sailors from the USS Ronald Reagan (May 2011-Dec 2013).
- A control group of 65,269 US Navy personnel was used for comparison.
Main Results:
- A relative risk (RR) of 9.2 for all malignancies was observed in the control population compared to US national data.
- The study suggests a significantly elevated cancer risk for sailors on nuclear-powered vessels.
- This elevated risk was not anticipated by existing radiation protection science.
Conclusions:
- Service on nuclear-powered ships may be associated with a higher risk of developing cancer.
- Current radiation protection legislation and scientific underpinnings may not fully address these occupational risks.
- Further research is warranted to understand and mitigate cancer risks in nuclear-ship environments.
Related Concept Videos
Cancer Prevention
7.5K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
7.5K
Biological Effects of Radiation
17.4K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
17.4K
Nuclear Fission
12.1K
Many heavier elements with smaller binding energies per nucleon can decompose into more stable elements that have intermediate mass numbers and larger binding energies per nucleon—that is, mass numbers and binding energies per nucleon that are closer to the “peak” of the binding energy graph near 56. Sometimes neutrons are also produced. This decomposition of a large nucleus into smaller pieces is called fission. The breaking is rather random with the formation of a large...
12.1K
Mutagenicity and Carcinogenicity
1.8K
Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...
1.8K
Cancer-Critical Genes II: Tumor Suppressor Genes
9.3K
Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
9.3K
Mutations
42.5K
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
42.5K

