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Updated: Dec 28, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Atrial fibrillation induced by peripherally inserted central catheters.
Reshma Golamari1, Yub Raj Sedhai2, Karthik Ramireddy3
1Department of Internal Medicine, Penn State Health Milton S. Hershey Medical CenterHersheyPennsylvania.
Peripherally inserted central catheters (PICCs) can cause arrhythmias if the tip migrates into the heart. Prompt retraction of the PICC tip resolved the atrial fibrillation in this case.
Area of Science:
- Cardiology
- Vascular Access Devices
Background:
- Peripherally inserted central catheters (PICCs) are central venous catheters (CVCs) inserted into peripheral veins, commonly used for long-term therapies like antibiotics and parenteral nutrition.
- PICCs offer a lower complication rate compared to traditional CVCs.
- However, PICC malpositioning has been linked to cardiac arrhythmias.
Observation:
- A case report details a patient experiencing atrial fibrillation.
- The arrhythmia was potentially triggered by the malpositioning of a PICC tip deep within the right atrium.
Findings:
- Migration of the PICC tip into the right atrium was suspected as the cause of atrial fibrillation.
- Mechanical irritation or stimulation of the right atrium by the catheter tip likely induced the arrhythmia.
Implications:
- This case highlights a rare but serious complication of PICC malpositioning.
- It underscores the importance of monitoring PICC tip placement to prevent cardiac arrhythmias.
- Prompt recognition and repositioning of malpositioned PICCs can effectively resolve associated arrhythmias.
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