Sequential Percutaneous Approach for Severe Mitral and Aortic Regurgitation

Area of Science:

• Cardiology
• Interventional Cardiology
• Cardiac Surgery

Background:

• Percutaneous approaches are established for high-surgical-risk patients with aortic stenosis and mitral regurgitation.
• Transcatheter aortic valve implantation (TAVI) use is expanding to various indications, including pure aortic regurgitation.

Observation:

• A 72-year-old woman with prohibitive surgical risk and extensive comorbidities, including chronic arterial dissection, presented with heart failure symptoms.
• Transthoracic echocardiography revealed severe functional mitral and aortic regurgitation.

Findings:

• The case demonstrates a challenging combined percutaneous intervention for severe multivalvular heart disease in a complex patient profile.
• This scenario represents a rare clinical situation with limited reported experience, particularly in inoperable patients.

Implications:

• Combined percutaneous treatment for multivalvular disease is feasible in select high-risk patients.
• This case expands the understanding of percutaneous interventions for complex valvular heart disease in patients unsuitable for surgery.
• Further research into combined percutaneous strategies for multivalvular disease is warranted.