Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

838
IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
838

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Illicit Drug Use on Facial Fracture Patterns and Hospital Resource Utilization.

Craniomaxillofacial trauma & reconstruction·2025
Same author

Evolving Use of Circulating Tumor DNA for HPV+ Oropharyngeal Carcinoma: Consensus Recommendations From the California Head and Neck Consortium.

JCO oncology practice·2025
Same author

Durability of Quality-of-Life Improvements Following Pediatric Septorhinoplasty.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2025
Same author

The Impact of Living in a Low Food Access/Low Income Area on Obstructive Sleep Apnea.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2024
Same author

Tumor Cell Stemness and Stromal Cell Features Contribute to Oral Cancer Outcome Disparity in Black Americans.

Cancers·2024
Same author

Patterns of Discordance Between Clinical and Pathologic Stage in Head and Neck Cancer.

The Laryngoscope·2024

Related Experiment Video

Updated: Dec 28, 2025

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.5K

Surgery versus Imaging in Non-Localizing Primary Hyperparathyroidism: A Cost-Effectiveness Model.

Ethan Frank1, WayAnne Watson2, Shannon Fujimoto2

  • 1Department of Otolaryngology, Loma Linda University Medical Center, Loma Linda, California, U.S.A.

The Laryngoscope
|February 18, 2020
PubMed
Summary

Advanced imaging for non-localizing primary hyperparathyroidism is more cost-effective than bilateral neck exploration. Utilizing advanced imaging techniques like SPECT, SPECT/CT, and 4D-CT offers significant cost savings and improved cure rates.

Keywords:
Hyperparathyroidismbilateral neck explorationcost-effectivenessminimally invasive parathyroidectomynon-localizing

More Related Videos

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.2K
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

4.6K

Related Experiment Videos

Last Updated: Dec 28, 2025

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.5K
Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.2K
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

4.6K

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Health Economics

Background:

  • Primary hyperparathyroidism (PHPT) management often involves challenges in localizing parathyroid adenomas.
  • Non-localizing PHPT typically requires bilateral neck exploration (BNE), a procedure with associated costs and potential for lower success rates.
  • Advanced imaging modalities are increasingly explored to improve diagnostic accuracy and surgical outcomes.

Purpose of the Study:

  • To conduct a cost-effectiveness analysis comparing advanced imaging techniques with primary bilateral neck exploration for non-localizing PHPT.
  • To evaluate the economic impact and success rates of different imaging-guided parathyroidectomy approaches.

Main Methods:

  • A decision tree model was employed for cost-effectiveness analysis.
  • Medicare financial data from 347 patients undergoing parathyroidectomy for PHPT were utilized.
  • Comparisons were made between bilateral neck exploration (BNE) and minimally invasive parathyroidectomy (MIP) guided by SPECT, SPECT/CT, and 4D-CT.

Main Results:

  • Bilateral neck exploration (BNE) costs $9578 with a 97.3% success rate.
  • SPECT+MIP: $8197 cost, 98.6% success.
  • SPECT/CT+MIP: $8271 cost, 98.9% success.
  • 4D-CT+MIP: $8146 cost, 99% success.
  • All advanced imaging approaches demonstrated negative incremental cost-effectiveness ratios (IECR) compared to BNE, indicating cost savings per percentage cure rate increase.

Conclusions:

  • Advanced imaging is cost-effective and associated with cost savings compared to routine bilateral neck exploration for non-localizing PHPT.
  • Increased imaging accuracy and decreased imaging costs further enhance cost-savings.
  • Optimizing procedural times (longer BNE, shorter MIP) also contributes to increased cost-effectiveness.