Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Functional specificity of thymus- dependent lymphocytes.

W E Paul, B Benacerraf

    Science (New York, N.Y.)
    |March 25, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Nobel laureates' letter to President Bush.

    The Washington post·2002
    Same author

    Three-dimensional prenatal diagnosis of frontonasal malformation and unilateral cleft lip/palate.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2002
    Same author

    Isolated major congenital heart disease.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2001
    Same author

    Variation in fetal femur length with respect to maternal race.

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine·2001
    Same author

    Isolated polydactyly: prenatal diagnosis and perinatal outcome.

    Prenatal diagnosis·2000
    Same author

    The prognostic significance of hyperextension of the fetal head detected antenatally with ultrasound.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2000
    Same journal

    Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

    Science (New York, N.Y.)·2026
    Same journal

    Local signals, systemic decline.

    Science (New York, N.Y.)·2026
    Same journal

    The mechanics of liver regeneration.

    Science (New York, N.Y.)·2026
    Same journal

    Computing in a memory with physics.

    Science (New York, N.Y.)·2026
    Same journal

    Retraction.

    Science (New York, N.Y.)·2026
    Same journal

    Making time.

    Science (New York, N.Y.)·2026
    See all related articles

    T lymphocytes, crucial for immune regulation and self-nonself discrimination, exhibit specific receptor interactions with thymus-dependent antigens and MHC gene products. This study explores how this complex specificity supports their regulatory and surveillance roles.

    Area of Science:

    • Immunology
    • Cell Biology

    Background:

    • Thymus-dependent (T) lymphocytes exhibit more restricted specificity compared to thymus-independent (B) lymphocytes.
    • T lymphocytes are key players in immune response regulation and distinguishing self from non-self.
    • T cells react to thymus-dependent protein/cell surface antigens and MHC gene products.

    Purpose of the Study:

    • To investigate the complex specificity patterns of T lymphocytes.
    • To relate T lymphocyte receptor interactions with antigens and MHC products to their regulatory and surveillance functions.

    Main Methods:

    • Analysis of T lymphocyte receptor interactions.
    • Correlation of specificity patterns with immune regulatory functions.

    Main Results:

    Related Experiment Videos

    • T lymphocytes possess receptors that interact with thymus-dependent antigens and MHC gene products.
    • These interactions can occur independently or as associated structures.

    Conclusions:

    • The complex specificity of T lymphocytes is intrinsically linked to their critical roles in immune regulation and surveillance.
    • Understanding these interactions is vital for comprehending immune system function.