Complications of measles: a case series
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Published on: January 7, 2019
Thelma Xerri1, Nicola Darmanin2, Maria Alessandra Zammit3
1Department of Medicine, Mater Dei Hospital, Msida, Malta thelmaxerri@gmail.com.
Abstract:
Measles, which was once thought to be a disappearing viral infection due to effective vaccination, has been re-emerging globally, with increasing cases in adolescents and adults. This has been attributed to anti-vaccination campaigning in the early 21st century, which has resulted in a drop in overall herd immunity. In this case series we report three patients with complications secondary to measles who presented to a hospital in Malta in 2019. Through this series, we discuss the range of possible complications caused by the measles virus, ranging from mild viraemic symptoms to multiorgan involvement which could possibly lead to high-dependency care and may even be fatal. We also highlight recent global statistics which reflect the exponential increase in the incidence of measles, with a special focus on Europe. It is emphasised that vaccine education and compliance with the two-dose measles vaccine should be implemented worldwide.
Insights
Measles is re-emerging globally due to decreased herd immunity from anti-vaccination campaigns. This case series highlights severe measles complications, emphasizing the need for worldwide vaccine education and compliance.
Area of Science:
- Infectious Diseases
- Public Health
- Virology
Background:
- Measles, a viral infection, was nearly eliminated by vaccination but is now re-emerging globally.
- Anti-vaccination campaigns have reduced herd immunity, leading to increased measles cases in adolescents and adults.
- Measles complications can range from mild symptoms to fatal multiorgan involvement.
Observation:
- A case series from Malta in 2019 reported three patients with measles complications.
- Complications ranged from mild symptoms to severe multi-organ involvement requiring high-dependency care.
Findings:
- Measles virus can cause a spectrum of illness, including potentially fatal outcomes.
- Global measles incidence, particularly in Europe, shows an exponential increase.
Implications:
- Urgent need for enhanced vaccine education and adherence to the two-dose measles vaccination schedule worldwide.
- Re-emergence of measles poses a significant public health threat, necessitating renewed vaccination efforts.
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