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GRASP55: A Multifunctional Protein
Hongrong Wu1, Tianjiao Li2, Jianfeng Zhao3
1Institute of Pathogenic Biology, Hengyang Medical College, University of South China, Hengyang, China.
Abstract:
GRASP55 was first found as Golgi cisternae stacking protein. Due to the crucial role of Golgi in vesicular trafficking and protein modification, GRASP55 was found to function in these two aspects. Further investigation revealed that GRASP55 also participates in the unconventional secretory pathway under stress. Moreover, GRASP55 is involved in autophagy initiation and autophagosome maturation, as well as cell activity.
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