Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

701
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
701
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

699
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
699
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

456
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
456
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

1.5K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.5K
Neuroplasticity01:01

Neuroplasticity

1.4K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
1.4K
Cognitive Learning01:21

Cognitive Learning

926
Cognitive learning is based on purposive behavior, incidental learning, and insight learning.
E. C. Tolman's theory of purposive behavior emphasizes that much behavior is goal-directed. He argued that to understand behavior, we must look at the entire sequence of actions leading to a goal. For instance, high school students study hard, not just due to past reinforcement but also to achieve the goal of getting into a good college.
Tolman introduced the idea that behavior is influenced by...
926

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prospective observational study of the effect of catheter ablation among patients with heart failure with preserved ejection fraction and persistent atrial fibrillation: Findings from BENEFIT-HFpEF.

Heart and vessels·2026
Same author

Psychosocial Factors Associated with Help-Seeking Intention Among Adults in Rural Japan.

Yonago acta medica·2026
Same author

Non-functional allele of <i>RESTORER OF FERTILITY 4</i> is functional for the reduction of <i>orf288</i> RNA in <i>japonica</i> rice.

Plant biotechnology (Tokyo, Japan)·2026
Same author

Combination of color-related genes regulates pigment composition and establishes diverse coloration in soybean.

Plant physiology and biochemistry : PPB·2026
Same author

Optimizing chemotherapy regimens and dosing for older patients with metastatic pancreatic cancer: insights from the Tokushukai real-world data project.

BMC cancer·2026
Same author

Negative Impact of Coronavirus Disease 2019 Pandemic on Gastric Cancer Care in Japan: A Tokushukai Real-World Data Project 08 (TREAD 08).

JGH open : an open access journal of gastroenterology and hepatology·2025

Related Experiment Video

Updated: Dec 28, 2025

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
07:01

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

5.1K

A program of exercise, brain training, and lecture to prevent cognitive decline.

Minoru Kouzuki1, Toshiaki Kato2, Kenji Wada-Isoe3,4

  • 1Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University, 86, Nishi-cho, Yonago, 683-8503, Japan.

Annals of Clinical and Translational Neurology
|February 19, 2020
PubMed
Summary

A community program combining exercise, cognitive training, and education significantly improved cognitive and physical functions in elderly individuals with mild cognitive decline.

More Related Videos

Orienteering as a Tool for Cognitive Research: An Implementation Guide
07:13

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Published on: November 29, 2024

1.4K
A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.3K

Related Experiment Videos

Last Updated: Dec 28, 2025

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
07:01

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

5.1K
Orienteering as a Tool for Cognitive Research: An Implementation Guide
07:13

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Published on: November 29, 2024

1.4K
A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.3K

Area of Science:

  • Gerontology
  • Neuroscience
  • Public Health

Background:

  • Mild cognitive decline (MCD) affects many elderly individuals.
  • Early intervention is crucial for managing cognitive decline and maintaining quality of life.

Purpose of the Study:

  • To evaluate the effectiveness of a community-based program on cognitive and physical functions in elderly individuals with suspected MCD.
  • The program integrated physical exercise, cognitive training, and health education.

Main Methods:

  • A crossover open-label trial involving 141 community-dwelling elderly participants with suspected MCD.
  • Participants were divided into two groups: intervention-first/observation-second (INT-OBS) and observation-first/intervention-second (OBS-INT).
  • The intervention comprised 6 months of weekly 2-hour sessions including physical exercise, cognitive training, and educational classes.

Main Results:

  • Significant improvements in Touch Panel-type Dementia Assessment Scale (TDAS) scores were observed during the intervention period compared to the observation period for all participants.
  • The OBS-INT group showed significant improvements in certain physical functions during their intervention phase.
  • The program demonstrated a positive impact on cognitive function as measured by TDAS scores.

Conclusions:

  • The community-based program effectively enhanced both cognitive and physical functions in elderly individuals experiencing suspected mild cognitive decline.
  • This integrated approach offers a promising strategy for promoting brain health and functional independence in aging populations.