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Age-related auditory brainstem response (ABR) threshold changes in the dancer mouse mutant
1Department of Oto-Rhino-Laryngology, University Hospital, Umeå, Sweden.
Acta Oto-Laryngologica
|November 1, 1988
Abstract:
An age-related analysis of auditory brainstem response (ABR) thresholds in 42 heterozygotic dancer mouse mutants (1-13 months old) showed an impairment of ABR thresholds with increasing age, though individual threshold curves could vary considerably. As compared with normal CBA/CBA mice, a progressive deterioration of ABR thresholds occurred from the 2nd postnatal month onwards. The dancer mutant has an inner ear with a morphogenetic type of defect, caused by a semidominant gene which is located in chromosome 19.