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Post-operative functional neurological symptom disorder after anesthesia.
Ryan S D'Souza1, Matthew N P Vogt1, Edwin H Rho1
1Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Functional neurological symptom disorder (FNSD) can occur after anesthesia. This study found FNSD often affects females with psychiatric history, appearing only post-operatively.
Area of Science:
- Neurology
- Anesthesiology
- Psychiatry
Background:
- Functional neurological symptom disorder (FNSD) is rare but can manifest post-anesthesia.
- Symptoms are neurological but not explained by medical conditions.
Observation:
- A case series of six patients experiencing FNSD post-general anesthesia.
- Literature search identified 38 additional cases of post-anesthetic FNSD.
Findings:
- Most patients were female (86%) with prior psychiatric history (49%) and FNSD history (53%).
- General anesthesia was common (93%); many underwent diagnostic tests and received pharmacologic therapy.
- Unanticipated hospital (53%) or ICU admission (25%) occurred, though no deaths were reported.
Implications:
- Findings inform anesthesia literature on FNSD presentation, risk factors, and outcomes.
- Anesthetic agents may predispose vulnerable individuals to FNSD symptoms.
- Understanding FNSD post-anesthesia aids in patient management and risk assessment.
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