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Adolescent diabetic amyotrophy.

P C Seddon1, C S Smith

  • 1Department of Child Health, Royal Liverpool Children's Hospital, Alder Hey, UK.

Acta Paediatrica Scandinavica
|November 1, 1988
PubMed
Summary
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Diabetic amyotrophy, a painful nerve condition, was observed in a 16-year-old with type 1 diabetes. This case is the first reported instance in this age group, highlighting a rare complication.

Area of Science:

  • Neurology
  • Endocrinology
  • Diabetology

Background:

  • Insulin-dependent diabetes mellitus (Type 1 diabetes) is a chronic condition requiring lifelong management.
  • Diabetic amyotrophy (lumbosacral polyradiculopathy) is a known complication of diabetes, typically affecting older adults.
  • This condition involves painful, asymmetrical weakness and muscle wasting, primarily in the lower limbs.

Observation:

  • A 16-year-old male with a five-year history of type 1 diabetes presented with severe diabetic ketoacidosis.
  • Following recovery from a cardiorespiratory arrest, the patient developed symptoms consistent with diabetic amyotrophy.
  • Clinical presentation included painful, asymmetrical weakness and wasting of proximal lower limb muscles.

Findings:

  • Cerebrospinal fluid analysis revealed elevated protein levels.

Related Experiment Videos

  • Electromyography demonstrated characteristic findings of neurogenic damage.
  • The patient's age at onset (16 years) is notably younger than previously reported cases.

    • Implications:

    • This case expands the known age range for diabetic amyotrophy.
    • It underscores the importance of recognizing rare diabetic complications in adolescents.
    • Further research may be needed to understand the pathophysiology and risk factors in younger populations.