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Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
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Social innovation in diagnostics: three case studies.

Megan L Srinivas1, Eileen J Yang2,3, Priyanka Shrestha3,4

  • 1Institute for Global Health & Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. megan.srinivas@unchealth.unc.edu.

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Social innovation enhances access to diagnostics in low- and middle-income countries. Novel community-driven approaches improve disease identification and linkage to care.

Keywords:
Crowdsourcing, HIV testingDiagnosticsMalaria, HPV cervical testingSocial innovation

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Area of Science:

  • Global Health
  • Public Health Innovation
  • Health Systems Research

Background:

  • Diagnostics are crucial for disease control but face access barriers in many regions.
  • Social innovation offers a framework to expand diagnostic access, particularly in the Global South.
  • Defined as novel, community-driven implementation of public health tools.

Purpose of the Study:

  • To explore the potential of social innovation in improving diagnostic accessibility.
  • To demonstrate the impact of social innovation across diverse health contexts.
  • To argue for the utility of social innovation in low- and middle-income countries (LMICs).

Main Methods:

  • Case study analysis of three diverse examples.
  • Malaria testing in schools (Malawi).
  • Cervical human papillomavirus (HPV) self-collection (Peru).
  • Crowdsourced human immunodeficiency virus (HIV) testing (China).

Main Results:

  • Social innovation interventions increased diagnostic uptake in Malawi, Peru, and China.
  • These approaches demonstrated effectiveness across varied geographic, cultural, and health system settings.
  • The principles applied are adaptable to other contexts for improved diagnostic delivery.

Conclusions:

  • Social innovation significantly boosts diagnostic uptake and accessibility in LMICs.
  • Adaptable tools and principles can address public health challenges and improve disease management.
  • This approach offers a unique opportunity to enhance health system performance and patient outcomes.