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Related Experiment Video

Updated: Dec 28, 2025

Real-time Monitoring of High Intensity Focused Ultrasound HIFU Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound HMIFU
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Elements Selection for Transcostal HIFU Refocusing Method: Simulation Study.

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    Summary
    This summary is machine-generated.

    A new iterative sparse limited power deposition (LPD) algorithm reduces transducer use in high-intensity focused ultrasound (HIFU) treatments. This enables parallel imaging and motion tracking, improving safety and efficiency for treating tumors near ribs.

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    Area of Science:

    • Medical physics
    • Biomedical engineering
    • Acoustic imaging

    Background:

    • Treating tumors near ribs with high-intensity focused ultrasound (HIFU) is challenging due to rib interference.
    • Ribs absorb ultrasound energy, distorting beams and limiting therapeutic heating.
    • Existing limited power deposition (LPD) algorithms aim to mitigate these effects.

    Purpose of the Study:

    • To introduce a novel iterative sparse LPD (ISLPD) approach for HIFU treatments.
    • To reduce the number of excited transducers during HIFU while maintaining focal heating efficiency.
    • To enable parallel imaging and motion tracking during HIFU by freeing up transducer elements.

    Main Methods:

    • Developed an ISLPD algorithm using an iteratively reweighted penalty matrix for sparsity induction.
    • Employed semidefinite relaxation (SDR) to convert non-convex constraints to convex form.
    • Simulated a 1-MHz spherical phased-array targeting an inhomogeneous medium using finite-difference time-domain (FDTD) and bioheat transfer equation (BHTE) models.

    Main Results:

    • The ISLPD approach achieved efficient focal heating comparable to existing methods.
    • Significantly reduced the number of active transducers required for treatment.
    • Demonstrated the superiority of the optimization-based ISLPD over ray-tracing methods for element selection.

    Conclusions:

    • The ISLPD algorithm offers an efficient and safe method for HIFU tumor treatment obscured by ribs.
    • Reducing transducer usage enhances treatment safety and allows for parallel diagnostic procedures.
    • This optimization-based approach represents a significant advancement in HIFU therapy planning.