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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
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Related Experiment Video

Updated: Dec 28, 2025

A Mouse Model of Intestinal Partial Obstruction
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Update on chronic intestinal pseudo-obstruction.

Letizia Zenzeri1, Renato Tambucci2,3, Paolo Quitadamo4

  • 1Emergency Pediatric Department, Santobono-Pausilipon Children's Hospital, Naples.

Current Opinion in Gastroenterology
|February 20, 2020
PubMed
Summary
This summary is machine-generated.

Chronic intestinal pseudo-obstruction (CIPO) is a severe gastrointestinal motility disorder. Recent advances offer improved diagnosis and management strategies for this rare condition.

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Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Pediatric Gastroenterology

Background:

  • Chronic intestinal pseudo-obstruction (CIPO) is a severe, disabling gastrointestinal dysmotility.
  • It mimics mechanical intestinal obstruction due to impaired coordinated propulsive activity.
  • Recent years have seen significant progress in managing this rare disorder.

Purpose of the Study:

  • To summarize current literature on CIPO management.
  • Focus on novelties in definition, epidemiology, diagnosis, and therapeutics.
  • Highlight distinctions between adult and pediatric CIPO.

Main Methods:

  • Narrative review of existing literature.
  • Focus on recent advancements and consensus criteria.
  • Analysis of diagnostic and therapeutic options.

Main Results:

  • Consensus on classification and diagnostic criteria for pediatric CIPO.
  • Distinct features identified between adult and pediatric forms.
  • Promising results in diagnostic testing and therapeutic interventions reported.

Conclusions:

  • No single diagnostic test is pathognomonic for CIPO.
  • No universally recommended drug treatment exists for improving motility.
  • Recent findings may aid in diagnosis and management of CIPO patients.