First Case of High-Level Azithromycin-Resistant Neisseria gonorrhoeae in North Carolina
Elizabeth L Palavecino1, Abdullah Kilic1, Matthew W Schmerer2
1From the Department of Pathology, Wake Forest School of Medicine and Wake Forest Baptist Health, Winston-Salem, NC.
Abstract:
We report on the first high-level azithromycin-resistant Neisseria gonorrhoeae isolate (minimum inhibitory concentration, ≥256 microg/mL) in North Carolina isolated from a pharyngeal swab of a 33-year-old HIV-negative man who has sex with men. In addition, the isolate was found to be susceptible to cefixime, ceftriaxone, and penicillin and resistant to tetracycline. By whole-genome sequencing, the strain was assigned as MLST ST9363, NG-MAST ST5035, and a novel NG-STAR sequence type, ST1993.
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