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Updated: Dec 28, 2025

Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
Published on: May 6, 2018
[The 474th case: anemia, ostealgia, proteinuria]
1Department of Hematology, Multiple Myeloma Medical Center of Beijing, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100043, China.
This case highlights a rare diagnosis of acquired Fanconi Syndrome (FS) linked to smoldering multiple myeloma (MM). Renal biopsy confirmed light chain proximal tubulopathy (LCPT), a challenging condition to identify.
Area of Science:
- Nephrology
- Hematology
- Pathology
Background:
- Acquired Fanconi Syndrome (FS) can be associated with plasma cell disorders.
- Smoldering multiple myeloma (MM) is an asymptomatic precursor to active MM.
- Monoclonal gammopathy of renal significance (MGRS) encompasses various kidney diseases caused by monoclonal proteins.
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