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GP73 facilitates hepatitis B virus replication by repressing the NF-κB signaling pathway

Long Liu1, Jianyong Zhu1, Jing Yang1

  • 1School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, China.

Journal of Medical Virology
|February 21, 2020
PubMed
Summary

Hepatitis B virus (HBV) infection increases Golgi protein 73 (GP73) production, which in turn promotes HBV replication by suppressing immune responses. GP73 may be a novel target for treating chronic hepatitis B.

Keywords:
Golgi protein 73acute viral infectionchronic viral infectionhepatitis B virushepatocellular carcinomanuclear factor-kappa B p50

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