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Updated: Dec 28, 2025

Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
The modified Allen test and a novel objective screening algorithm for hand collateral circulation using differential
Ahmed Elwali1, Zahra Moussavi1,2
1Biomedical Engineering Program, University of Manitoba, Winnipeg, Canada.
A new differential photo-plethysmography (PPG) method offers an objective way to screen hand artery patency, reducing risks associated with hand artery procedures. This technique identifies potential blockages and guides safer artery selection.
Area of Science:
- Vascular Surgery
- Medical Devices
- Diagnostic Techniques
Background:
- Hand artery cannulation and grafting carry risks of ischemia and thrombosis.
- Current screening methods like the Modified Allen Test (MAT) lack objectivity or availability.
- Objective screening is crucial for reducing complications in hand artery interventions.
Purpose of the Study:
- To introduce a novel, objective, reliable, and inexpensive method for screening hand arterial patency.
- To develop an artery selection algorithm based on differential photo-plethysmography (PPG) measurements.
- To evaluate the efficacy of PPG in assessing hand blood circulation and identifying risks.
Main Methods:
- Conducted a pilot study on 11 participants undergoing the Modified Allen Test (MAT).
- Recorded differential photo-plethysmography (PPG) measurements from thumb and little fingers of both hands.
- Applied a proprietary artery selection algorithm to analyze PPG data for each hand.
Main Results:
- The PPG method demonstrated results congruent with known vascular anatomy.
- Identified two participants with >50% blood reduction due to arterial occlusion.
- Indicated an elevated risk of accessing an artery in 8 out of 11 participants.
Conclusions:
- Differential PPG measurement combined with an artery selection algorithm shows promise as an objective screening tool.
- This method may offer insights into hand blood circulation and the impact of arterial occlusion.
- Further validation in larger studies could establish this technique for safer artery access selection.
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