Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lung Capacity01:47

Lung Capacity

55.9K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
55.9K
Pulmonary Function Tests01:25

Pulmonary Function Tests

654
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
654
Respiratory Volumes and Capacities I01:26

Respiratory Volumes and Capacities I

1.5K
Assessing the respiratory rate and rhythm for a complete minute is crucial for evaluating the breathing pattern. Even a minor increase in the patient's average respiratory rate, by as little as three to five breaths per minute, is an early and vital indicator of respiratory distress. Patients with a respiratory rate exceeding twenty-four breaths per minute require close monitoring to determine the physiological alterations. This careful observation is essential for prompt recognition and...
1.5K
Respiratory Volumes and Capacities01:22

Respiratory Volumes and Capacities

4.6K
The respiratory system is responsible for the intake of oxygen and the expulsion of carbon dioxide from the body. Respiratory volumes describe the volume of air in the lungs at different phases of the respiratory cycle. Tidal volume is the air breathed in and out during normal, quiet breathing. Inspiratory reserve volume is the air that can be forcefully inspired beyond the tidal volume. In contrast, expiratory reserve volume refers to the air that can be expelled from the lungs after a normal...
4.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of a Lifestyle Risk Index With Visceral and Subcutaneous Adipose Tissue in the German National Cohort (NAKO).

Obesity (Silver Spring, Md.)·2025
Same author

Adiposity, mortality, and disease risk: insights from bioimpedance analysis and magnetic resonance imaging.

BMC medicine·2025
Same author

Birth Order, Caesarean Section, or Daycare Attendance in Relation to Child- and Adult-Onset Type 1 Diabetes: Results from the German National Cohort.

International journal of environmental research and public health·2022
Same author

The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers.

BMC genomics·2017
Same author

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.

The Lancet. Neurology·2017
Same author

Organic speciation of ambient quasi-ultrafine particulate matter (PM<sub>0.36</sub>) in Augsburg, Germany: Seasonal variability and source apportionment.

The Science of the total environment·2017

Related Experiment Video

Updated: Dec 28, 2025

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

1.2K

[Lung function in the German National Cohort: methods and initial results].

Stefan Karrasch1,2,3, Annette Peters4, Christa Meisinger5,6

  • 1Institut für Epidemiologie, Helmholtz Zentrum München, München, Deutschland. stefan.karrasch@med.uni-muenchen.de.

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
|February 21, 2020
PubMed
Summary

This study presents lung function data from the German National Cohort, revealing expected spirometry and exhaled nitric oxide (FeNO) levels. Findings highlight smoking's impact on lung function and FeNO in German adults.

Keywords:
AsthmaCOPDFeNOGerman National CohortSpirometry

More Related Videos

Generation of Human 3D Lung Tissue Cultures 3D-LTCs for Disease Modeling
05:47

Generation of Human 3D Lung Tissue Cultures 3D-LTCs for Disease Modeling

Published on: February 12, 2019

21.8K
Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models
03:38

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models

Published on: June 20, 2025

757

Related Experiment Videos

Last Updated: Dec 28, 2025

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

1.2K
Generation of Human 3D Lung Tissue Cultures 3D-LTCs for Disease Modeling
05:47

Generation of Human 3D Lung Tissue Cultures 3D-LTCs for Disease Modeling

Published on: February 12, 2019

21.8K
Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models
03:38

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models

Published on: June 20, 2025

757

Area of Science:

  • Pulmonology
  • Epidemiology
  • Public Health

Background:

  • Germany lacked nationwide, standardized lung function data.
  • The German National Cohort (GNC) was established to address this gap.
  • This work details lung function assessments within the GNC.

Purpose of the Study:

  • To describe lung function testing methods in the GNC.
  • To present initial results from the GNC Midterm Baseline Dataset.
  • To establish a basis for future respiratory health research in Germany.

Main Methods:

  • Lung function assessment included spirometry (Level 1) and exhaled nitric oxide (FeNO, Level 2).
  • Rigorous quality assurance involved standardized training, interim evaluations, and equipment calibration.
  • Spirometry quality control utilized a stepwise offline analysis of raw flow-volume curves.

Main Results:

  • Data from 101,734 participants (86,893 spirometry, 15,228 FeNO).
  • Average spirometry Z-scores (FEV1, FVC, FEV1/FVC) were within expected ranges.
  • Current smoking decreased FeNO by 43%; respiratory allergy increased FeNO by 16% in nonsmokers.

Conclusions:

  • Spirometry and FeNO results align with expected distributions and correlates.
  • The GNC provides a robust dataset for studying respiratory health determinants.
  • This cohort is crucial for future research on respiratory disease prevention in Germany.