The role of imaging in malignant pleural mesothelioma: an update after the 2018 BTS guidelines
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S Sinha1, A J Swift2, M A Kamil1
1Department of Radiology, Sheffield Teaching Hospitals, Sheffield, UK.
Abstract:
Malignant pleural mesothelioma (MPM) is a primary malignancy of the pleura and is associated with a poor outcome. The symptoms and signs of malignant mesothelioma present late in the natural history of the disease and are non-specific, making the diagnosis challenging and imaging key. In 2018, the British Thoracic Society (BTS) updated the guideline on diagnosis, staging, and follow-up of patients with MPM. These recommendations are discussed in this review of the current literature on imaging of MPM. It is estimated MPM will continue to cause serious morbidity and mortality in the UK late into the 21st century, and internationally, people continue to be exposed to asbestos. We aim to update the reader on current and future imaging strategies, which could aid early diagnosis of pleural malignancy and provide an update on staging and assessment of tumour response.
Insights
Malignant pleural mesothelioma (MPM) diagnosis is challenging due to late, non-specific symptoms. This review updates on imaging strategies for early MPM diagnosis, staging, and treatment response assessment.
Area of Science:
- Oncology
- Radiology
- Pulmonology
Background:
- Malignant pleural mesothelioma (MPM) is a rare but aggressive cancer with a poor prognosis.
- Diagnosis is often delayed due to non-specific symptoms and late presentation.
- Asbestos exposure remains a significant risk factor globally.
Purpose of the Study:
- To review current and future imaging strategies for MPM.
- To provide an update on the diagnosis, staging, and follow-up of MPM.
- To highlight the importance of imaging in early detection and management.
Main Methods:
- Review of current literature on MPM imaging.
- Discussion of British Thoracic Society (BTS) 2018 guidelines.
- Focus on diagnostic, staging, and response assessment imaging modalities.
Main Results:
- Imaging plays a crucial role in the challenging diagnosis of MPM.
- Current guidelines emphasize specific imaging protocols for staging and follow-up.
- Future imaging techniques may improve early detection and treatment monitoring.
Conclusions:
- MPM continues to pose a significant health burden, necessitating improved diagnostic tools.
- Advanced imaging is essential for timely diagnosis, accurate staging, and effective management of MPM.
- Continued research into novel imaging strategies is vital for improving patient outcomes.
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