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Related Concept Videos

Visual Agnosia01:12

Visual Agnosia

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Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
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An Informant-Based Simple Questionnaire for Visuospatial Dysfunction Assessment in Dementia.

Ching-Tsu Wang1, Guang-Uei Hung2, Cheng-Yu Wei3

  • 1Department of Neurology, Tainan Municipal Hospital, Tainan, Taiwan.

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|February 22, 2020
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Summary

A new visuospatial dysfunction (VSD) questionnaire effectively screens for dementia with Lewy bodies (DLB). The HAI-VSQ tool showed high accuracy and practicality for clinical use in identifying VSD in DLB patients.

Keywords:
Alzheimer’s diseasecognitive abilitiesdementia with Lewy bodiesscreening toolsvisuospatial dysfunction

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Area of Science:

  • Neurology
  • Geriatrics
  • Psychometry

Background:

  • Visuospatial dysfunction (VSD) is a key diagnostic symptom in dementia with Lewy bodies (DLB).
  • Accurate and practical screening tools for VSD in DLB are needed for early diagnosis and management.

Purpose of the Study:

  • To validate a novel visuospatial dysfunction questionnaire, the HAI-VSQ.
  • To establish a cutoff score for screening VSD in dementia with Lewy bodies (DLB).

Main Methods:

  • Retrospective analysis of data from the HAICDDS project.
  • Comparison of HAI-VSQ with CASI-Draw and MoCA-VS in non-demented controls (NDC), Alzheimer's disease (AD), and DLB participants.

Main Results:

  • The HAI-VSQ demonstrated higher scores in DLB compared to NDC and AD participants, even after age adjustment.
  • A cutoff score of ≥ 2 on HAI-VSQ achieved 0.77 sensitivity and 0.94 specificity for DLB screening.
  • HAI-VSQ showed minimal influence from demographic factors and correlated strongly with the CDR scale, significantly discriminating DLB from AD and NDC.

Conclusions:

  • The novel HAI-VSQ is a practical and effective screening tool for VSD in DLB.
  • The questionnaire is suitable for both clinical practice and research registration platforms.