Scurvy: A New Old Cause of Skeletal Pain in Young Children

Christel Chalouhi1, Nayla Nicolas2, Nancy Vegas1

  • 1General Pediatrics Department, Necker Hospital, Paris, France.

Frontiers in Pediatrics
|February 22, 2020
PubMed

Insights

Scurvy in children, a historical disease, presented with skeletal pain mimicking infections or cancers. Delayed diagnosis occurred due to unfamiliarity among pediatricians and radiologists.

Area of Science:

  • Pediatrics
  • Nutritional Deficiencies
  • Radiology

Background:

  • Scurvy, a vitamin C deficiency disease, is historically significant but rarely diagnosed in contemporary pediatrics.
  • This report details three pediatric cases of scurvy presenting with non-specific symptoms.

Observation:

  • Three children aged approximately three years were admitted with severe skeletal pain and malaise.
  • Initial presentations mimicked infectious or malignant conditions, leading to extensive diagnostic workups.
  • Dietary selectivity was not the primary factor identified in these cases.

Findings:

  • The diagnosis of scurvy was significantly delayed in all three cases.
  • Bone imaging, including X-ray and MRI, revealed typical scurvy lesions retrospectively.
  • Pediatricians and radiologists lacked familiarity with scurvy, hindering prompt diagnosis.

Implications:

  • Increased awareness of scurvy is crucial for pediatricians and radiologists to avoid diagnostic delays.
  • Recognizing scurvy's atypical presentations can prevent unnecessary investigations and treatments.
  • This highlights the importance of considering historical diagnoses in modern clinical practice.

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