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Scurvy: A New Old Cause of Skeletal Pain in Young Children
Christel Chalouhi1, Nayla Nicolas2, Nancy Vegas1
1General Pediatrics Department, Necker Hospital, Paris, France.
Insights
Scurvy in children, a historical disease, presented with skeletal pain mimicking infections or cancers. Delayed diagnosis occurred due to unfamiliarity among pediatricians and radiologists.
Area of Science:
- Pediatrics
- Nutritional Deficiencies
- Radiology
Background:
- Scurvy, a vitamin C deficiency disease, is historically significant but rarely diagnosed in contemporary pediatrics.
- This report details three pediatric cases of scurvy presenting with non-specific symptoms.
Observation:
- Three children aged approximately three years were admitted with severe skeletal pain and malaise.
- Initial presentations mimicked infectious or malignant conditions, leading to extensive diagnostic workups.
- Dietary selectivity was not the primary factor identified in these cases.
Findings:
- The diagnosis of scurvy was significantly delayed in all three cases.
- Bone imaging, including X-ray and MRI, revealed typical scurvy lesions retrospectively.
- Pediatricians and radiologists lacked familiarity with scurvy, hindering prompt diagnosis.
Implications:
- Increased awareness of scurvy is crucial for pediatricians and radiologists to avoid diagnostic delays.
- Recognizing scurvy's atypical presentations can prevent unnecessary investigations and treatments.
- This highlights the importance of considering historical diagnoses in modern clinical practice.
Abstract:
We report 3 cases of scurvy in children that occurred during a short period (2018) in a general pediatrics unit of a tertiary hospital for children in Paris. All children were around 3 years of age and were admitted for skeletal pain and altered general state, which mimicked infectious or malignant diseases. Their selective diet was not the prominent issue. The diagnosis of scurvy was delayed, after too many unnecessary examinations and medications. Bone imaging findings (X-ray and MRI) were a posteriori considered typical, but lesions were not easily identified as scurvy lesions because scurvy is not well-known by pediatricians and radiologists who should be mindful of this historical diagnosis.
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