A 67-Year-Old Male with Diffuse Purpuric Vesicles and Bullae.

Area of Science:

• Dermatology
• Pathology

Background:

• Leukocytoclastic vasculitis (LCV) is a common small-vessel vasculitis affecting postcapillary venules.
• Typical LCV presents as purpuric lesions on the shins, often triggered by infections, medications, or systemic diseases.

Observation:

• Uncommon LCV presentations include bullae and ulcers.
• This case details bullous LCV with grouped vesicles on the face and body.

Findings:

• The bullous LCV mimicked varicella-zoster infection.
• Facial and widespread bullous lesions are atypical for LCV.

Implications:

• Recognizing atypical LCV presentations is crucial for accurate diagnosis.
• This case expands the differential diagnosis for vesicular eruptions, particularly on the face.