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Chitosan based bioactive materials in tissue engineering applications-A review.
Md Minhajul Islam1, Md Shahruzzaman1, Shanta Biswas1
1Department of Applied Chemistry and Chemical Engineering, Faculty of Engineering and Technology, University of Dhaka, Dhaka, 1000, Bangladesh.
Bioactive Materials
|February 22, 2020
Summary
Innovative chitosan-based bioactive materials offer solutions for tissue engineering. Their unique properties enable tailored development for clinical applications, addressing limitations of traditional materials.
Area of Science:
- Biomaterials Science
- Tissue Engineering
- Polymer Chemistry
Background:
- Bioactive materials are crucial for tissue engineering but often brittle and difficult to shape.
- There's a need for materials with tunable properties and predictable degradation.
- Chitosan-based materials present an ideal alternative due to their versatility.
Purpose of the Study:
- To review scientific findings on chitosan-based bioactive materials in tissue engineering.
- To highlight advancements in constituents, fabrication, and properties.
- To provide an outlook on future clinical applications.
Main Methods:
- Literature review of recent scientific findings.
- Analysis of chitosan-based material properties (structural, bioactive, mechanical).
- Examination of fabrication technologies and constituent combinations.
Main Results:
- Chitosan offers excellent formability, fabricability, biocompatibility, and biodegradability.
- Innovative chitosan composites demonstrate tailored physical, biological, and mechanical characteristics.
- These materials show potential for overcoming limitations of conventional tissue engineering scaffolds.
Conclusions:
- Chitosan-based bioactive materials are promising for tissue engineering.
- Advancements in fabrication and composition enhance their suitability for clinical use.
- These materials represent a realistic future alternative for regenerative medicine.
