Cortactin Expression in Hematopoietic Cells: Implications for Hematological Malignancies.

Ramón Castellanos-Martínez1, Karina E Jiménez-Camacho1, Michael Schnoor1

  • 1Department of Molecular Biomedicine, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Mexico City, Mexico.

Summary

Cortactin, a protein regulating cell adhesion and migration, is now functionally expressed in hematopoietic cells. Its overexpression in leukemia correlates with poor prognosis and treatment failure.

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