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Reducing cardiovascular risk among people living with HIV: Rationale and design of the INcreasing Statin Prescribing

Sae Takada1, Allison J Ober2, Judith S Currier3

  • 1Division of General Internal Medicine and Health Services Research, Department of Medicine, Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA, USA.

Progress in Cardiovascular Diseases
|February 22, 2020
PubMed

Insights

Cardiovascular disease (CVD) risk is high in people with HIV (PLWH). A new study uses behavioral economics to boost statin prescribing, aiming to improve heart health for this population.

Area of Science:

  • Implementation Science
  • Behavioral Economics
  • Public Health

Background:

  • Cardiovascular disease (CVD) is a significant cause of illness in people living with HIV (PLWH).
  • Statins are effective in reducing CVD risk for PLWH but are under-prescribed.
  • Barriers exist at organizational, clinician, and patient levels for statin uptake.

Purpose of the Study:

  • To address under-prescription of statins in PLWH.
  • To implement and evaluate educational and behavioral economics interventions to increase statin uptake.
  • To assess implementation outcomes, including acceptability and cost.

Main Methods:

  • Stepped-wedge cluster randomized trial (INSPIRE study).
  • Focus on community health clinics serving diverse PLWH in Los Angeles.
  • Interventions include education and behavioral economics-informed clinician feedback.

Main Results:

  • Study is ongoing; results not yet available.

Conclusions:

  • Effective strategies are needed to increase statin prescribing for PLWH.
  • Implementation science and behavioral economics offer promising approaches.
  • Improving CVD prevention in PLWH is a critical public health goal.

Keywords:
Behavioral economicsCardiovascular diseaseHIVImplementation scienceStatins

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