Microperimetric Biofeedback Training after Successful Inverted Flap Technique for Large Macular Hole

Area of Science:

• Ophthalmology
• Retinal Surgery
• Visual Neuroscience

Background:

• Large macular hole (LMH) surgery often results in suboptimal visual recovery despite high closure rates.
• Microperimetric biofeedback shows promise in enhancing visual function for macular conditions.
• The efficacy of biofeedback post-inverted flap technique for LMH requires further investigation.

Purpose of the Study:

• To evaluate the effectiveness of microperimetric biofeedback in improving macular function after successful LMH surgery using the inverted flap technique.
• To compare visual acuity, retinal sensitivity, and fixation stability between patients receiving biofeedback and a control group.

Main Methods:

• A prospective comparative study involving 26 patients who underwent LMH surgery.
• Patients were divided into two groups: a trained group receiving microperimetric biofeedback and a control group receiving standard care.
• Evaluated visual acuity, macular sensitivity (MS), central macular sensitivity (CMS), and fixation stability over 12 months.

Main Results:

• While visual acuity showed improvement in both groups, no significant difference was observed.
• Significant improvements in macular sensitivity (MS) were noted only in the trained group (p=0.01).
• Central macular sensitivity (CMS) and fixation stability showed significantly greater improvement in the biofeedback-trained group compared to the control group (p=0.004 for CMS).

Conclusions:

• Microperimetric biofeedback consolidates and enhances the gains in retinal sensitivity and fixation achieved after successful inverted flap surgery for LMH.
• Biofeedback training offers a valuable adjunct to improve visual function and stability in patients recovering from LMH surgery.