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Updated: Dec 28, 2025

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Problem solving in clinical practice: the sick infant with low sodium and high potassium
Yincent Tse1,2, Nidhi Singhal3, Leigh McDonald4
1Department of Paediatric Nephrology, Great North Children's Hospital, Newcastle upon Tyne, UK yincenttse@nhs.net.
Abstract:
Many paediatricians will be faced with a sick infant who on investigation is found to have hyponatraemia and hyperkalaemia at some time in their career. The focus of initial management includes the treatment of potentially life-threatening hyperkalaemia with concurrent investigation aiming to elucidate whether the underlying cause reflects a primarily renal or endocrine pathology. We describe the presentation of two infants who each presented with one of the more common underlying diagnoses that led to this biochemical disturbance and discuss the approach to immediate treatment, diagnostic work-up and longer term management.
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