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Assessment of peripheral blood cell inflammatory markers in patients with chronic subdural hematoma
Yadong Zhang1, Yi Yang1, Shengrong Long1
1Department of Neurosurgery, First Affiliated Hospital of China Medical, University, Shenyang, China.
Objectives:
We aimed to study the role of peripheral blood cell inflammatory markers in patients with chronic subdural hematoma (CSDH).
Patients And Methods:
We enrolled 466 patients with CSDH and 150 healthy controls and retrospectively analyzed peripheral blood cell inflammatory markers, including neutrophils, platelets, lymphocytes, neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR). Subsequently, we performed a subgroup analysis of the patients with CSDH based on gender, age, trauma history, and unilateral or bilateral hematoma.
Results:
The CSDH group had higher numbers of neutrophils and platelets, as well as a higher NLR and PLR, than those in the healthy control group. Further, compared with the healthy control group, the CSDH group had lower lymphocyte counts. Subgroup analysis indicated trauma history as the only significant factor.
Conclusion:
Peripheral blood cell inflammatory markers could serve as indexes for evaluating the inflammatory state in patients with CSDH. There is a need for further studies on the prognostic role of this index in patients with CSDH.
