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Effect of Vitamin D and Magnesium Supplementation on Behavior Problems in Children with Attention-Deficit

Mostafa Hemamy1, Motahar Heidari-Beni2, Gholamreza Askari1

  • 1Department of Community Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.

International Journal of Preventive Medicine
|February 25, 2020
PubMed

Insights

Vitamin D and magnesium supplements significantly improved conduct, social, and anxiety behaviors in children with attention-deficit hyperactivity disorder (ADHD). However, these nutrients did not impact psychosomatic issues.

Area of Science:

  • Nutritional Neuroscience
  • Pediatric Psychiatry
  • Clinical Nutrition

Background:

  • Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder with inattention, hyperactivity, and impulsivity.
  • Nutritional factors are increasingly implicated in ADHD pathology.
  • This study investigates the impact of Vitamin D and magnesium on ADHD behaviors.

Purpose of the Study:

  • To examine the effects of combined Vitamin D and magnesium supplementation on behavioral problems in children diagnosed with ADHD.
  • To evaluate the efficacy of nutrient supplementation in managing ADHD symptoms.

Main Methods:

  • A double-blind, randomized controlled trial involving 66 children with ADHD.
  • Participants received Vitamin D (50,000 IU/week) and magnesium (6 mg/kg/day) or placebo for 8 weeks.
  • Conners' Parent Rating Scale assessed behavioral changes at baseline and study conclusion.

Main Results:

  • Serum levels of 25-hydroxy-Vitamin D3 and magnesium increased significantly in the intervention group.
  • Supplementation led to significant reductions in conduct problems, social problems, and anxiety/shyness scores.
  • No significant effect was observed on psychosomatic problem scores.

Conclusions:

  • Combined Vitamin D and magnesium supplementation effectively improved conduct, social, and anxiety/shyness symptoms in children with ADHD.
  • The supplementation did not significantly affect psychosomatic problem scores.
  • Nutrient interventions show promise for managing specific behavioral aspects of ADHD.
Abstract

Keywords:
Attention-deficit disorder with hyperactivityVitamin Dmagnesiumrandomized clinical trial

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