Cardiac Thrombus Formation During Cardiopulmonary Resuscitation for Cardiac Arrest: Is It Time for

Cesare de Gregorio1, Alessio Stanzione1

  • 1Department of Clinical and Experimental Medicine, Cardiology Unit, Postgraduate Residency School on Cardiovascular Diseases, University Hospital G. Martino, Messina, Italy.

Insights

Current guidelines consider thrombosis a cause of cardiorespiratory arrest. This case study shows cardiac thrombus formation is a consequence of cardiac standstill, resolving with heparin and CPR.

Area of Science:

  • Cardiology
  • Critical Care Medicine
  • Pathophysiology

Background:

  • Current guidelines suggest thrombosis may cause cardiorespiratory arrest (CA).
  • Cardiac thrombus formation (TF) is often considered a consequence, not a cause, of cardiac standstill.
  • Infective endocarditis can lead to severe complications, including cardiac events.

Observation:

  • A young male patient with infective endocarditis experienced sudden cardiac arrest (CA).
  • During cardiopulmonary resuscitation (CPR), echocardiography revealed unexpected thrombus formation in the right atrium.
  • The patient achieved return of spontaneous circulation after 16 minutes of CPR.

Findings:

  • The cardiac thrombus resolved rapidly with intravenous heparin administration and continued chest compressions.
  • This case challenges the traditional view of thrombosis as a primary cause of CA.
  • Echocardiography played a crucial role in diagnosing and managing the cardiac thrombus during resuscitation.

Implications:

  • Cardiac thrombus formation may be a consequence of circulatory arrest rather than a cause.
  • Early recognition and treatment of cardiac thrombus during CPR can be life-saving.
  • Cardiac ultrasound may prove valuable in managing cardiorespiratory arrest patients, despite not being routine.

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