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Corynebacterium Striatum, an Emerging Nosocomial Pathogen: Case Reports

Priya Datta1, Varsha Gupta1, Menal Gupta1

  • 1Department of Microbiology, Government Medical College and Hospital, Sector-32, Chandigarh, India.

Infectious Disorders Drug Targets
|February 25, 2020
PubMed
Abstract

Insights

Corynebacterium striatum infections can be mistaken for contamination. Accurate identification using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) is crucial for diagnosing this emerging nosocomial pathogen.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Clinical Diagnostics

Background:

  • Corynebacterium striatum is an emerging nosocomial pathogen.
  • It can cause various infections, particularly in immunocompromised and hospitalized patients.
  • Distinguishing true infection from contamination is a clinical challenge.

Observation:

  • Three cases of C. striatum infection were initially misidentified as contamination.
  • Clinical suspicion, considering predisposing factors, was essential.

Findings:

  • Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) enabled accurate identification.
  • This technique was key to implicating C. striatum as the causative agent.

Implications:

  • Highlights the importance of accurate identification of C. striatum.
  • Emphasizes the need for clinical suspicion in cases of potential contamination.
  • Underscores the role of advanced techniques like MALDI-TOF MS in diagnosing emerging pathogens.
Keywords:
Corynebacterium striatumMALDIcase report.diphtheroidnosocomialpneumoniawound infection

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