Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Common arterial trunk with pulmonary atresia.

D E Schofield1, R H Anderson

  • 1Department of Pathology, Children's Hospital of Pittsburgh, Pennsylvania.

International Journal of Cardiology
|August 1, 1988
PubMed
Summary

This study details a rare congenital heart defect featuring a single arterial trunk supplying the body and a hypoplastic pulmonary artery system, indicating a common arterial trunk with pulmonary atresia. This finding offers new insights into complex congenital heart disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pulmonary infiltrates with eosinophilia syndromes in children.

The Journal of pediatrics·2000
Same author

Renovascular hypertension in Marfan syndrome.

Pediatric nephrology (Berlin, Germany)·1997
Same author

Giant cell ependymoma of the filum terminale. A report of two cases.

The American journal of surgical pathology·1996
Same author

A quantitative study of nerve distribution in the conduction system of the guinea pig heart.

Journal of anatomy·1996
Same author

The development of the atrioventricular junction in the human heart.

Circulation research·1996
Same author

Loss of heterozygosity at chromosome regions 22q11-12 and 11p15.5 in renal rhabdoid tumors.

Genes, chromosomes & cancer·1996

Area of Science:

  • Cardiovascular Pathology
  • Congenital Heart Disease
  • Pediatric Cardiology

Background:

  • Congenital heart disease encompasses a range of structural abnormalities present at birth.
  • Common arterial trunk is a rare defect where a single great artery arises from the heart, supplying both systemic and pulmonary circulations.
  • Pulmonary atresia involves the underdevelopment or absence of the pulmonary valve and artery, severely restricting blood flow to the lungs.

Observation:

  • A congenitally malformed heart presented with a solitary arterial trunk originating from the heart base, supplying coronary and systemic arteries.
  • Pulmonary blood supply was primarily via systemic to pulmonary collateral arteries.
  • Hypoplastic intrapericardial pulmonary arteries were observed in each lung hilum, with discontinuity likely due to dissection, but a connection to the solitary trunk indicated pulmonary atresia.

Related Experiment Videos

Findings:

  • The heart exhibited a usual atrial arrangement and concordant atrioventricular connections.
  • A solitary arterial trunk supplied systemic and coronary arteries, with pulmonary circulation dependent on collateral arteries.
  • Evidence suggested an initial common trunk that evolved into pulmonary atresia, with hypoplastic pulmonary arteries.

Implications:

  • This case contributes to understanding the spectrum of common arterial trunk and associated pulmonary atresia.
  • The findings necessitate a review of current nomenclature and classification of complex congenital heart malformations.
  • Further research is needed to elucidate the developmental pathways and clinical management of such rare cardiac anomalies.