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Updated: Dec 27, 2025

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Timing between Breast Reconstruction and Oncologic Mastectomy-One Center Experience
Adelaida Avino1,2, Laura Răducu1,2, Lăcrămioara Aurelia Brînduşe3
1Department of Plastic and Reconstructive Surgery, "Prof. Dr. Agrippa Ionescu" Clinical Emergency Hospital, 011356 Bucharest, Romania.
Breast reconstruction after mastectomy significantly improves quality of life. Timing depends on cancer stage, with immediate reconstruction for early stages and delayed options for advanced stages, guided by a multidisciplinary team.
Area of Science:
- Oncology
- Plastic Surgery
- Quality of Life Studies
Background:
- Breast cancer is the most prevalent cancer in women, necessitating diverse therapeutic strategies.
- Mastectomy, a radical surgical intervention for breast cancer, profoundly impacts patients' quality of life.
- Breast reconstruction, either immediate or delayed, offers a means to enhance post-mastectomy quality of life.
Purpose of the Study:
- To evaluate the time interval between mastectomy and subsequent breast reconstruction.
- To analyze the relationship between breast cancer stage and reconstruction timing.
- To assess the influence of adjuvant therapies on reconstruction choices.
Main Methods:
- A retrospective study involving 57 female patients who underwent mastectomy and breast reconstruction.
- Data collected included tumor stage, lymph node status, and adjuvant chemoradiotherapy necessity.
- Analysis focused on descriptive statistics of reconstruction types and the median time between procedures.
Main Results:
- Immediate breast reconstruction was observed in Stage I and II breast cancer patients.
- Delayed reconstruction, initiated at least six months post-mastectomy, was common for advanced stages.
- Stage III patients underwent free flap reconstruction (50%) 8-43 months post-mastectomy; radiotherapy influenced latissimus dorsi flap with implant use (22.6%).
Conclusions:
- Breast reconstruction is crucial for improving the quality of life for mastectomy patients.
- Optimal timing for breast reconstruction requires collaborative decision-making among the patient, plastic surgeon, and oncologist.
- Personalized treatment plans considering cancer stage and adjuvant therapy are essential for successful breast reconstruction outcomes.
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