Related Experiment Videos
A new antifungal antibiotic, cystargin: fermentation, isolation, and characterization
M Uramoto1, Y Itoh, R Sekiguchi
1Antibiotics Laboratory, RIKEN, Institute of Physical and Chemical Research, Saitama, Japan.
The Journal of Antibiotics
|December 1, 1988
Abstract:
A new sulfur-containing peptide antifungal antibiotic, cystargin, was isolated from the fermentation broth of a new species of genus Kitasatosporia, designated as Kitasatosporia cystarginea. On acid hydrolysis, cystargin (C60H77N19O17S6) gave equimolar glycine, proline, aspartic acid and arginine. By performic acid oxidation, cysteic acid was detected after hydrolysis. It showed a growth inhibitory activity against various phytopathogenic fungi and inhibition of beta-1,3-glucan synthetase from Saccharomyces cerevisiae.