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Related Concept Videos

Human Genetics01:28

Human Genetics

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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
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Genetic Screens02:46

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Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
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Genome-wide Association Studies-GWAS01:11

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Animal Mitochondrial Genetics02:59

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Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
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Direct-to-Consumer Nutrigenetics Testing: An Overview.

Matteo Floris1,2, Antonella Cano1, Laura Porru1

  • 1Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43/b, 07100 Sassari, Italy.

Nutrients
|February 27, 2020
PubMed
Summary
This summary is machine-generated.

Direct-to-consumer genetic testing is expanding, offering personalized lifestyle and dietary advice based on genetic markers. This analysis of online nutrigenetics services reveals a need for quality standards and clear guidelines for consumers.

Keywords:
dietdirect-to-consumer genetic testing (DTC-GT)geneticnutrigeneticsnutrigenomicsnutrition

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Area of Science:

  • Nutrigenetics
  • Genetics
  • Personalized Nutrition

Background:

  • The proliferation of direct-to-consumer genetic testing services is driven by reduced genotyping and sequencing costs.
  • Online companies increasingly offer disease risk predictions and lifestyle recommendations based on genetic profiles.
  • Nutrigenetics services, which provide dietary advice linked to an individual's genetic makeup, are a growing segment of this market.

Purpose of the Study:

  • To analyze the landscape of online nutrigenetics services offered globally.
  • To assess the costs, genetic markers utilized, and scientific rigor of these services.
  • To identify the need for standardized guidelines in the direct-to-consumer nutrigenetics industry.

Main Methods:

  • Systematic analysis of online nutrigenetics services.
  • Evaluation of 45 companies worldwide offering genetic-based dietary recommendations.
  • Assessment of service costs, targeted nutritional traits, and scientific validity.

Main Results:

  • Significant variation exists in the cost and scope of online nutrigenetics services.
  • Services often rely on a limited number of genetic markers for dietary pattern determination.
  • The scientific precision and quality standards of proposed services vary considerably.

Conclusions:

  • The direct-to-consumer nutrigenetics market requires greater transparency and scientific validation.
  • Establishment of minimum quality standards and regulatory guidelines is essential.
  • Consumers need clear information to critically evaluate the scientific basis of personalized nutrition advice.