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[Rosette-forming peripheral lymphocytes, in children with measles]
Insights
Measles infection depresses cellular immunity, reducing T lymphocytes in children. Malnutrition severity impacts the recovery of these vital immune cells post-infection.
Area of Science:
- Immunology
- Pediatrics
- Infectious Diseases
Abstract:
During measles infection in human beings, depression of cellular immunity appears. The authors studied several groups of children with measles complaining of various degrees of malnutrition in terms of rosette forming lymphocytes in peripheral blood; marked reduction of T lymphocytes were seen in all of the groups during the acute stage of the disease, that persisted up to two weeks after the exanthematous stage. When comparison was established of eutrophic and 1st degree malnourished children with those affected with 3rd degree malnutrition, differences were found in the recovery of the number of rosett-E forming cells.