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Long-Term Outcome of Common Femoral Artery Endarterectomy In Octogenarians and Non-Octogenarians
Christian Uhl1, Hannah Götzke2, Florian Zeman3
1Clinic of Vascular Surgery, Krankenhaus Barmherzige Brüder Regensburg, Pruefeningerstrasse 81, Regensburg, 93049, Germany.
Insights
Common femoral artery endarterectomy is a safe procedure for treating arteriosclerotic disease, offering excellent long-term results. However, octogenarians face higher risks for perioperative mortality and major amputation.
Area of Science:
- Vascular Surgery
- Arterial Disease Management
- Geriatric Cardiovascular Health
Background:
- Arteriosclerotic disease of the common femoral artery (CFA) necessitates intervention.
- Surgical versus endovascular approaches are available for CFA disease.
- Limited data exist on surgical outcomes in elderly patients.
Purpose of the Study:
- To evaluate the safety and efficacy of common femoral artery endarterectomy (CFAE) in elderly patients.
- To compare outcomes between patients younger than 80 years and those 80 years or older.
- To identify risk factors influencing outcomes after CFAE.
Main Methods:
- Retrospective analysis of 977 CFAEs performed between March 2007 and July 2018.
- Patients were divided into two groups: <80 years (Group 1) and ⩾80 years (Group 2).
- Primary endpoints included patency rates, limb salvage, and overall survival.
Main Results:
- Thirty-day mortality was significantly higher in Group 2 (7.6%) compared to Group 1 (1.6%).
- Major amputation rates at 30 days were also higher in Group 2 (2.9%) versus Group 1 (0.7%).
- While limb salvage was comparable, overall survival was significantly lower in octogenarians (15.7%) versus younger patients (59.1%).
Conclusions:
- Common femoral artery endarterectomy demonstrates excellent long-term patency and limb salvage rates.
- Octogenarians undergoing CFAE experience increased perioperative mortality and major amputation risks.
- Female gender, advanced age, and critical limb ischemia indicators are associated with poorer outcomes, while statin use may improve survival.
Objective:
Arteriosclerotic disease of the common femoral artery can be treated by surgical or endovascular intervention. Elderly patients are said to have a worse outcome if treated by surgical means; however, data to support this theory are missing.
Methods:
Retrospective analysis of all patients who underwent common femoral artery endarterectomy between March 2007 and July 2018 in our clinic. Group 1 included all patients <80 years and Group 2 included all patients ⩾80 years. Endpoints were patency rates, limb salvage, and overall survival.
Results:
During this time period, 977 common femoral artery endarterectomies were performed. Indication was claudication in 61.5% and critical limb ischemia in 38.5%. Group 1 included 805 cases (82.4%) and Group 2 included 172 cases (17.6%). Thirty-day mortality was 2.7% (Group 1 = 1.6% versus Group 2 = 7.6%; p < 0.001) and 30-day major amputation was 1.1% (Group 1 = 0.7% versus Group 2 = 2.9%; p = .043). Primary patency and secondary patency were 84.2% and 96.8%, respectively, after 7 years. Limb salvage (93.7%, Group 1 = 94.1% versus Group 2 = 91.8%; p = .088) and overall survival (52.0%, Group 1 = 59.1% versus Group 2 = 15.7%; p = .006) were significantly different after the same time period. Multivariable analysis showed female gender to be a risk factor for loss of primary patency. Age ⩾ 80 years and ulcer or gangrene were risk factors for death. Statin use was beneficial to survival.
Conclusions:
Common femoral artery endarterectomy is a safe procedure with excellent long-term results. Octogenarians have an increased risk for perioperative mortality and major amputation.
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