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Updated: Dec 27, 2025
Synthesis and Reaction Chemistry of Nanosize Monosodium Titanate
Published on: February 23, 2016
Prostate Cancer Cellular Uptake of Ternary Titanate Nanotubes/CuFe2O4/Zn-Fe Mixed Metal Oxides Nanocomposite
Ahmed Ag El-Shahawy1, S A Abdel Moaty2, A H Zaki1
1Materials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef, Egypt.
Background:
Certainly, there is a demand for stronger recognition of how nanoparticles can move through the cell membrane. Prostate cancer is one of the forcing sources of cancer-relevant deaths among men.
Aim Of The Work:
The current research studied the power of prostate cancer cells to uptake a ternary nanocomposite TNT/CuFe2O4/Zn-Fe mixed metal oxides (MMO).
Methodology:
The nanocomposite was synthesized by a chemical method and characterized by a High-resolution transmission electron microscope, Field emission scanning electron microscope, X-ray diffraction, Fourier transmission infra-red, X-ray photoelectron spectroscopy, dynamic light scattering. Besides, it was implemented as an inorganic anticancer agent versus Prostate cancer PC-3 cells.
Results:
The results revealed cellular uptake validity, cell viability reduction, ultra-structures alterations, morphological changes and membrane damage of PC-3 cells.
Conclusion:
The prepared ternary nanocomposite was highly uptake by PC-3 cells and possessed cytotoxicity that was dose and time-dependent. To conclude, the study offered the potential of the investigated ternary nanocomposite as a promising prostate anticancer agent.
