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Recurrent respiratory papillomatosis: a 10 year study

B Benjamin1, D S Parsons

  • 1Royal Alexandra Hospital for Children, Sydney, Australia.

The Journal of Laryngology and Otology
|November 1, 1988
PubMed

Insights

Recurrent respiratory papillomatosis can present in infancy, earlier than previously known. Pediatric onset shows better control rates but requires more surgeries than adult onset, with no major anesthetic complications.

Area of Science:

  • Otolaryngology
  • Pediatric Pulmonology
  • Laryngology

Background:

  • Recurrent respiratory papillomatosis (RRP) is a rare disease characterized by wart-like growths in the airway.
  • Previous literature has not extensively detailed early infantile onset of RRP.

Purpose of the Study:

  • To review treatment outcomes for RRP in children and adults over a decade.
  • To identify any correlation between age of onset and disease control.
  • To assess anesthetic safety and surgical complications.

Main Methods:

  • Retrospective review of 60 RRP cases treated over 10 years.
  • Analysis of patient demographics, age of onset, treatment outcomes, and complications.
  • Detailed endoscopic examination of the upper aerodigestive tract under general anesthesia.

Main Results:

  • Fifteen percent of patients presented with symptoms by two months of age, indicating an earlier onset than previously reported.
  • Pediatric onset RRP had a 66% control rate, compared to 44% for adult onset, but required more surgical interventions.
  • No anesthetic deaths or major complications occurred; glottic webs were the sole surgical complication.

Conclusions:

  • RRP can manifest in early infancy, necessitating earlier diagnostic considerations.
  • While pediatric onset RRP is more challenging surgically, it demonstrates better overall control.
  • Comprehensive endoscopic evaluation is crucial for accurate diagnosis and management of RRP.

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